EFFICACY OF MIDOSTAURINE IN ACUTE MYELOID LEUKEMIA WITH FLT-3 MUTATION
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Abstract
Detection of FLT3-ITD mutation in patients with acute myeloid leukemia (AML) is associated with a poor prognosis and is an indication to transplantation of allogeneic hematopoietic stem cells in the first remission. Midostaurin is the first FLT3 inhibitor approved ny for the treatment of patients with AML with FLT3 mutation.
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