REGENERATIVE ENDODONTICS-CHALLENGES AND FUTURE DIRECTION
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Abstract
Thus, there is a considerable interest in research and clinical studies aimed towards regeneration of a functional and healthy pulp- dentin complex.1, 2 The goal of Regenerative Dentistry is to induce biologic replacement of dental tissues and their supporting structures. The potential for regenerative dentistry is in large part due to advancements in biologic therapies that apply growth and differentiation factors which hasten or induce natural biologic regeneration. Most of the concepts have emerged from the growing fields of tissue engineering, which emphasizes the spatial assembly of distinct stem cells, growth factors and scaffolds to form a functional tissue or organ.3. Utilization of stem cells to regenerate the lost pulpal tissue may thereby reverse the tissue to its normal state.
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